Hematologic Malignancies are cancers that begin in blood forming tissues such as Bone marrow or in
the cells of the immune system.
1.Leukemia
2.Lymphoma
3.Multiple Myeloma
(ALL, AML, CLL, CML, MM, MDS, etc.)
Common Types of B-Cell Malignancies:-
Chronic lymphocytic leukemia
Diffuse Large B-cell lymphoma
Follicular Lymphoma
Mantle cell lymphoma
Marginal zone lymphoma
Clinically defined hematologic malignancies specimens include:
Collection of fresh cancer blood and preparation of human viable blood cells or frozen PBMC pellets
Collection of cancer bone marrow aspirate and preparation of viable BMMC or frozen BMMC pellets
Preparation of cancer bone marrow FFPE ( Human Tumor Tissues) “Trephine biopsy FFPE and
paraffin-embedded BMMC pellets
Standard Specimen Format and Sets
Leukemia / Lymphoma Specimens
Cancer PBMC, snap-frozen pellet
Viable PBMC from cancer blood
Marker-specific PBMC (CD19, etc.)
Matching cancer serum, cancer plasma, cancer blood
Bone marrow aspirate, snap-frozen
Bone marrow Human Tumor Tissues”>trephine biopsy snap-frozen
Bone marrow FFPE from trephine biopsy
Bone marrow FFPE from cancer BMMC
Multiple Myeloma / MDS Specimens
Bone marrow aspirate, snap-frozen
Bone marrow Human Tumor Tissues”>trephine biopsy snap-frozen
Viable BMMC from cancer bone marrow
Cancer BMMC, snap-frozen
Marker-specific BMMC (CD138, etc.)
Matching cancer serum, cancer plasma
Bone marrow FFPE from trephine biopsy